Accommodation in Rome and Venice
Rome being one of the most preferred tourist destinations in the world has some of the best hotels that would guarantee you a comfortable stay. Keeping your requirements and budget in mind, I have found couple of great deals for you to check out. Here are my recommendations.

Una miriade di papaveri a Roma (Source: Geomangio)
About 100 metres from Rome's Cornelia Metro Station, Hotel Waldorf is located in a quiet residential area that is 30 minutes away from the Vatican City.

Vatican City (Source: davidMonroy)
Address: Via Andrea Alciato 14-16, Aurelio, 00167 Rome
Website: http://www.hotelwaldorf.net (Click the link for more information, pictures of the hotel and rooms and to make a reservation)
Rate: $122 per double room per night
Here is a review
The location was nice and quiet, close to metro station, and the hotel staff was friendly and helpful.
(Source: Booking.com: Hotel Waldorf, Rome, Italy - 1244 Guest reviews. Book your hotel now!)
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Hotel Athena is located in the University area of Rome, 2 km from downtown and 1 km from the main station. It is a simple hotel offering you comfort and hospitality you might need. The Rooms are well equipped with all the facilities you need.
Other than that , it offers you a bar (7PM-10PM) which serves great drinks,a travel desk assisting you in your tours , public garage and private transfer from and to airport .
Here's a video giving you a better picture of the hotel :Video clip of Hotel Athena in Siena by Eurobookings.com
A visitor had to say this about the place:“athena in siena”
Tariff: The price begins from $134 per night.Book here!
Check In/Check Out: 12PM/11AM
Address: P Mascagni 55, 53100 Siena, Italy
Tel: 0577 286313