Best Destinations For an All-Girls Vacation in the USA 

Asheville, is one of the most enchanting cities in the USA. Such is the beauty of the place, that it is believed that anyone who visits the city, ends up moving here. It is a truly eclectic, comfy and beautiful mountain city. Although at a 15 hr drive from Boston, the flights here are very cheap and convenient.

Asheville, NC (Source: David Wilson)

Here is a recent tourist review,

This was our first visit to Asheville, and we loved it so much we want to move there! People are friendly and polite. The whole atmosphere is peaceful and laid back. Nature and "natural" are huge in this town. Between the awe-inspiring mountain views and the Blue Ridge Parkway, Asheville has no lack of scenery! So many outdoor activities and trails, it's awesome. The "green" support is great too. I can't neglect to mention the abundance of above-average resturants... A true "foodtopia!" We ate at a different place every afternoon and evening, and each resturant was impressive.

(Source: City of Asheville)

Asheville (Source: Jeff Gunn)

Whether you spend the day hiking in the Blue Ridge Parkway, or climbing the Great Smoky Mountains, you will not be at a loss of crisp, fresh air. The city also has a number of waterfalls. You can also visit the underground limestone Linville Caverns. For the indoor lovers, there is always a combination of historic sights like Thomas Wolfe Memorial, or the artistic Folk Art center. Also, the Spas and massage centers keep you relaxed throughout the trip. 

Myrtle Beach is a coastal city with long and continuous stretch of beaches. The climate here is mild and seductive all year round, and the city is full of endless fun, entertainment and relaxation. This is one of the most selected options for a fabulous vacation in complete serenity. The flights are extremely cheap from Boston to Myrtle Beach.

Myrtle Beach (Source: Curtis and Eric)

Here's a snippet from a travel site,

Myrtle Beach has long been hailed as one of America's most family-friendly beach destinations and for good reason-it's convenient and affordable, not to mention beautiful and studded with golf courses and beaches. A hefty selection of attractions, ranging from golf (of the miniature or professional variety) to amusement parks and Vegas-esque showcases, draws crowds rain or shine. Of course, the wide, white sand beaches and picturesque dunes don't hurt, either!

(Source: AOL Travel)

Myrtle Beach Skywheel (Source: Claire)

The main activity here is lying around on beaches, basking in the sun, and chilling in the clean sea water. You can also visit the Springmaid Beach Pier, which is a beach landmark, or the huge Brookgreen Gardens. Another popular activity is The Carolina Opry, which has four perennially running shows, or the Myrtle Beach Skywheel, which stretches 200 ft. above the ground.

Not to be confused with the one in New Jersey, Ocean City (Maryland) is a a unique destination with exotic white sand beaches, a warm weather. The famous Ocean City Maryland Boardwalk, buzzes with activities, to keep you relaxed and entertained. Located at around 8 hour drive from Boston, this is an excellent place for a small trip.

Ocean City ocean view (Source: Bernt Rostad)

Here is a snippet,

Ocean City Maryland - what a great, unique vacation beach resort! The weather in Ocean City is warm and inviting, the ocean and white sand beaches sparkling. The famous Ocean City Maryland Boardwalk buzzes with activity and the entertainment is unsurpassed.

(Source: Ocean City)

Ocean City Boardwalk (Source: Bernt Rostad)

There are a number of activities to indulge in here. Be it the Boardwalk, which is one of the best places in the city, the lovely beach, the Frontier Town amusement park, or the Northside Park, the attractions here are lovely and very interesting.